Description

Maitotoxin CAS NO 59392-53-9 is a potent marine polyether toxin, recognized as one of the most powerful non-proteinaceous natural products. Its complex structure and extreme biological activity make it a critical reference standard and research tool in toxicology and pharmacology. This high-purity compound is essential for researchers in academic institutions, pharmaceutical R&D, and specialized analytical laboratories studying ion channel function, neurotoxicity mechanisms, and marine biotoxin detection.

Application

• Pharmacological Research: Used as a potent and selective activator of calcium-permeable non-selective cation channels to study cellular calcium signaling pathways.
• Toxicology Studies: Serves as a high-potency reference toxin for investigating the mechanisms of action of marine biotoxins and assessing their toxicological profiles.
• Neuroscience Research: Employed as a tool compound to probe the function of neuronal ion channels and receptors involved in excitotoxicity.
• Analytical Standard: Acts as a certified reference material (CRM) for the calibration of analytical equipment (e.g., LC-MS) in the detection and quantification of marine toxins in seafood safety monitoring.
• Drug Discovery: Utilized in high-throughput screening assays to identify novel antagonists or modulators of its target channels for potential therapeutic development.
• Biochemical Reagent: Applied in controlled experimental settings to induce specific cellular responses for studying downstream biochemical events.

Basic Information

Product Name	Maitotoxin
CAS No.	59392-53-9
Molecular Formula	C164H256O68S2Na2
Molecular Weight	3424.6 g/mol (Disodium salt form)
Synonyms	MTX; Maitotoxin-1; MTX-1; Gambiertoxin; Ciguatoxin-3C; Marine Polyether Toxin; 3,4,34,50,51,52,53,54,55,56,57,58,59,60,61,62,63,64,65,66,67,68,69,70,71,72,73,74,75,76,77,78,79,80,81,82,83,84,85,86,87,88,89,90,91,92,93,94,95,96,97,98,99,100,101,102,103,104,105,106,107,108,109,110,111,112,113,114,115,116,117,118,119,120,121,122,123,124,125,126,127,128,129,130,131,132,133,134,135,136,137,138,139,140,141,142,143,144,145,146,147,148,149,150,151,152,153,154,155,156,157,158,159,160,161,162,163,164-Octadecahydro-2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80,83,86,89,92,95,98,101,104,107,110,113,116,119,122,125,128,131,134,137,140,143,146,149,152,155,158,161,164-octacosaoxa-1,4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61,64,67,70,73,76,79,82,85,88,91,94,97,100,103,106,109,112,115,118,121,124,127,130,133,136,139,142,145,148,151,154,157,160,163-hexapentacontaen-6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72,75,78,81,84,87,90,93,96,99,102,105,108,111,114,117,120,123,126,129,132,135,138,141,144,147,150,153,156,159,162-pentapentacontaone Disodium Salt
EINECS	Contact for details

Quality Control

Our Maitotoxin is produced and handled under strict quality-controlled conditions suitable for research applications. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and stability. A detailed Certificate of Analysis (COA) is provided, which includes data from techniques such as HPLC, LC-MS, and NMR spectroscopy to confirm the high purity and structural integrity of this sensitive reference material.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, consider storage under an inert atmosphere or in a desiccated environment. Allow the vial to equilibrate to room temperature in a dry atmosphere before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to reference standard
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 5.0 %
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.