Description

2-Amino-3-Piperazin-1-Ylpyrazine is a high-purity heterocyclic organic compound featuring a pyrazine core substituted with amino and piperazinyl groups. This specific molecular architecture makes it a valuable and versatile building block (synthon) for advanced chemical synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for creating new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Serves as a core scaffold for developing new generation pesticides, herbicides, and fungicides with improved efficacy and selectivity.
• Chemical Biology Probe: Used in academic and industrial research to create molecular probes for studying enzyme function and biological pathways.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis and material science applications.
• Custom Synthesis Building Block: Supplied to contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.

Basic Information

Product Name	2-Amino-3-Piperazin-1-Ylpyrazine
CAS No.	59215-43-9
Molecular Formula	C8H14N6
Molecular Weight	194.24 g/mol
Synonyms	2-Amino-3-(1-piperazinyl)pyrazine; 3-Piperazin-1-ylpyrazin-2-amine; 2-Amino-3-piperazin-1-yl-pyrazine; 1-(2-Aminopyrazin-3-yl)piperazine; Pyrazinamine, 3-(1-piperazinyl)-; 59215-43-9; 2-Amino-3-(piperazin-1-yl)pyrazine
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Piperazin-1-Ylpyrazine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.