Description

Piperazine, 2,6-Diethynyl- (9Ci) is a specialized heterocyclic building block characterized by its piperazine core functionalized with ethynyl groups. This compound matters as a high-value intermediate for advanced organic synthesis, enabling the construction of complex molecular architectures, particularly in pharmaceutical and materials science research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty polymer industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research pipelines.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and pesticides with tailored activity profiles.
• Ligand and Catalyst Development: Serves as a precursor for creating sophisticated chelating ligands and organometallic catalysts used in asymmetric synthesis.
• Polymer and Material Science: Monomer for synthesizing specialty polymers, dendrimers, and advanced materials with unique thermal or electronic properties.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological systems and diagnostic applications.
• Cross-coupling Reactions: The ethynyl groups make it a valuable substrate for Sonogashira and other palladium-catalyzed cross-coupling reactions.

Basic Information

Product Name	Piperazine, 2,6-Diethynyl- (9Ci)
CAS No.	59157-12-9
Molecular Formula	C8H8N2
Molecular Weight	132.16 g/mol
Synonyms	2,6-Diethynylpiperazine; 1,4-Diazacyclohexane, 2,6-diethynyl-; 2,6-Bis(ethynyl)piperazine; Piperazine, 2,6-diethynyl-; 2,6-Diethynyl-1,4-diazacyclohexane
EINECS	Contact for details

Quality Control

Every batch of Piperazine, 2,6-Diethynyl- (9Ci) is produced and tested under strict quality management protocols to ensure consistency and reliability for research and development applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) and easily oxidized nature, this material should be stored under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.