Description

10-Piperazino-8-(Methylsulfonyl)-10,11-Dihydrodibenzo[B,F]Thiepin 5-Oxide is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial interest for its role in the research and development of novel therapeutic agents, particularly within the central nervous system (CNS) and psychiatric drug pipelines. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of proprietary active pharmaceutical ingredients (APIs).

Application

• Key Intermediate in CNS Drug Synthesis: Serves as a critical building block in the development of novel psychotropic and neuroactive pharmaceutical compounds.
• Research Chemical for Pharmacology: Used in academic and industrial research to study structure-activity relationships (SAR) and receptor binding profiles.
• Precursor for Active Pharmaceutical Ingredients (APIs): Employed in multi-step synthetic routes to produce candidate drug molecules for clinical trials.
• Process Chemistry & Scale-Up: Utilized in process optimization and pilot-scale production for new chemical entities (NCEs).
• Reference Standard: Provides a high-purity standard for analytical method development, validation, and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	10-Piperazino-8-(Methylsulfonyl)-10,11-Dihydrodibenzo[B,F]Thiepin 5-Oxide
CAS No.	58868-87-4
Molecular Formula	C21H24N2O3S2
Molecular Weight	416.56 g/mol
Synonyms	8-(Methylsulfonyl)-10-piperazino-10,11-dihydrodibenzo[b,f]thiepin 5-oxide; Dibenzo[b,f]thiepin, 10,11-dihydro-8-(methylsulfonyl)-10-(1-piperazinyl)-, 5-oxide; 10-(1-Piperazinyl)-8-(methylsulfonyl)-10,11-dihydrodibenzo[b,f]thiepin 5-oxide; Zotepine Intermediate; Zotepine Related Compound; CAS 58868-87-4
EINECS	Contact for details

Quality Control

Our production of 10-Piperazino-8-(Methylsulfonyl)-10,11-Dihydrodibenzo[B,F]Thiepin 5-Oxide adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our quality systems are designed to support cGMP compliance for pharmaceutical applications, ensuring traceability and reliability for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.