Description

(R)-2-Phenylpiperidine Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant commercial importance. Its enantiomerically pure structure is critical for the development of active pharmaceutical ingredients (APIs) and fine chemicals where stereochemistry dictates biological activity. This compound is essential for research and manufacturing in the pharmaceutical, agrochemical, and advanced material sectors.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the synthesis of central nervous system (CNS) active drugs, receptor modulators, and other bioactive molecules.
• Asymmetric Catalysis: Used as a precursor or ligand in the development of chiral catalysts for stereoselective synthesis.
• Agrochemical Research: Serves as a building block for novel, enantiomerically pure pesticides and herbicides.
• Academic & R&D: Fundamental compound for medicinal chemistry research, process development, and studying structure-activity relationships (SAR).
• Fine Chemical Production: Employed in the multi-step synthesis of complex organic molecules requiring specific (R)-configuration.

Basic Information

Product Name	(R)-2-Phenylpiperidine Hydrochloride
CAS No.	58613-58-4
Molecular Formula	C11H15N·HCl
Molecular Weight	197.71 g/mol (Free base: 161.24 g/mol)
Synonyms	(R)-2-Phenylpiperidine HCl; (R)-2-Phenylpiperidine Hydrochloride Salt; (R)-2-Phenylpiperidinium Chloride; (R)-α-Phenylpiperidine Hydrochloride; (2R)-2-Phenylpiperidine Hydrochloride; (R)-(+)-2-Phenylpiperidine Hydrochloride; (R)-2-Piperidylphenyl Hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-2-Phenylpiperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis (HPLC, Chiral GC), to ensure high enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) detailing identity, assay, impurity profile, and residual solvents are provided and can be tailored to meet specific pharmacopeial (USP/EP) or customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.