Description

7,8-Didehydro-3-(2,4-Dinitrophenoxy)-4,5α-Epoxy-17-Methylmorphinan-6α-Ol is a specialized morphinan derivative of significant interest in advanced pharmaceutical research and chemical synthesis. This compound serves as a critical intermediate or reference standard in the development and analytical profiling of opioid receptor ligands. It is primarily utilized by research institutions and pharmaceutical companies engaged in neuropharmacology, medicinal chemistry, and forensic analysis. The precise structure, featuring a dinitrophenoxy and epoxy moiety, makes it a valuable tool for studying structure-activity relationships and metabolic pathways.

Application

• Pharmaceutical Research Intermediate: A key building block in the synthetic pathways for novel opioid analgesics and antagonist compounds.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing of related active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Studies: Employed in research to investigate the binding affinity and functional activity at opioid receptor subtypes (μ, κ, δ).
• Metabolic Pathway Investigation: Serves as a substrate or standard in studies examining the biotransformation and pharmacokinetics of morphinan-based drugs.
• Forensic Analysis: Used as an analytical standard for the identification and quantification of controlled substances and their derivatives in forensic toxicology.
• Biochemical Tool Compound: Applied in vitro to probe neurological mechanisms and signal transduction pathways associated with the opioid system.

Basic Information

Product Name	7,8-Didehydro-3-(2,4-Dinitrophenoxy)-4,5α-Epoxy-17-Methylmorphinan-6α-Ol
CAS No.	58534-70-6
Molecular Formula	C24H23N3O7
Molecular Weight	465.46 g/mol
Synonyms	3-O-(2,4-Dinitrophenyl)-4,5α-epoxy-17-methylmorphinan-6α-ol; 6α-Hydroxy-3-(2,4-dinitrophenoxy)-4,5α-epoxy-17-methyl-6,7-didehydromorphinan; 3-(2,4-Dinitrophenoxy)-4,5α-epoxy-17-methyl-6,7-didehydromorphinan-6α-ol; 17-Methyl-3-(2,4-dinitrophenoxy)-4,5α-epoxy-6,7-didehydromorphinan-6α-ol; Dinitrophenoxymorphinan derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as purity, identity, and impurity profiles. We adhere to Good Manufacturing Practice (GMP) principles for research-grade chemicals, and our analytical methods, including HPLC and spectroscopy, are validated to ensure reliable and reproducible results for critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 1.0%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.