Description

2,5-Piperazinedione, 3,6-Bis(3-Aminopropyl)-, (3S-Cis)- (9Ci) is a specialized chiral piperazinedione derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional structure, featuring both diketopiperazine and terminal amine groups, makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptide mimetics, and sophisticated chemical libraries.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly in oncology and neurology research.
• Peptidomimetic Scaffold: Used to design and synthesize non-peptide compounds that mimic the structure and function of bioactive peptides.
• Ligand Synthesis: Serves as a precursor for creating chelating agents and specialized ligands in catalysis and material science.
• Polymer Modification: Employed to introduce functional amine groups into polymer backbones for creating advanced functional materials.
• Bioconjugation Chemistry: Utilized as a linker or spacer molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Academic & Industrial R&D: A valuable reagent for methodological development in asymmetric synthesis and heterocyclic chemistry.

Basic Information

Product Name	2,5-Piperazinedione, 3,6-Bis(3-Aminopropyl)-, (3S-Cis)- (9Ci)
CAS No.	58485-32-8
Molecular Formula	C10H20N4O2
Molecular Weight	228.29 g/mol
Synonyms	(3S,6S)-3,6-Bis(3-aminopropyl)piperazine-2,5-dione; (3S-cis)-3,6-Bis(3-aminopropyl)-2,5-piperazinedione; (S,S)-2,5-Diketo-3,6-bis(3-aminopropyl)piperazine; Bis(3-aminopropyl)-2,5-diketopiperazine (S,S-isomer); (S,S)-DKP-NH2; Chiral Diketopiperazine Diamine; L-Lysine derived diketopiperazine
EINECS	Contact for details

Quality Control

Our production of 2,5-Piperazinedione, 3,6-Bis(3-Aminopropyl)-, (3S-Cis)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity suitable for research and development applications. All materials are characterized by modern analytical techniques including HPLC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.