Description

Pyrazinecarbonyl Chloride, 5-Ethoxy- (9Ci) is a specialized heterocyclic building block and reactive intermediate of significant interest in advanced organic synthesis. Its core value lies in its ability to introduce the 5-ethoxy-pyrazinecarbonyl moiety, a key structural feature for modulating biological activity and material properties. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries who are developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in developing kinase inhibitors, antimicrobial agents, and other bioactive heterocycles.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the pyrazine scaffold contributes to efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as novel semiconductors or light-emitting components, due to its electron-deficient aromatic system.
• Chemical Biology Probes: Facilitates the development of activity-based probes and labeled compounds for studying biological pathways and target engagement.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis houses serving the life sciences sector with tailored, high-purity intermediates.

Basic Information

Product Name	Pyrazinecarbonyl Chloride, 5-Ethoxy- (9Ci)
CAS No.	58333-67-8
Molecular Formula	C7H7ClN2O2
Molecular Weight	186.60 g/mol
Synonyms	5-Ethoxypyrazine-2-carbonyl chloride; 5-Ethoxy-2-pyrazinecarbonyl chloride; 2-Pyrazinecarbonyl chloride, 5-ethoxy-; 5-Ethoxypyrazinecarbonyl chloride; Ethoxy-pyrazine-carbonyl chloride; 5-Ethoxy-pyrazine-2-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our Pyrazinecarbonyl Chloride, 5-Ethoxy- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring reproducible results in research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.