Description

n-[2-Nitro-4-(Trifluoromethyl)Phenyl]Piperazine is a specialized heterocyclic building block featuring a piperazine ring substituted with a nitro and trifluoromethyl phenyl group. This compound matters for its role as a key intermediate in the synthesis of advanced pharmaceutical agents and agrochemicals, where its unique structure imparts specific biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and anti-infective drugs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl and nitro groups.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential intermediate in the synthesis of specialty polymers, liquid crystals, or organic electronic materials.
• Dye and Pigment Intermediate: Can be utilized in the synthesis of complex, high-performance dyes and pigments due to its aromatic nitro component.

Basic Information

Product Name	n-[2-Nitro-4-(Trifluoromethyl)Phenyl]Piperazine
CAS No.	58315-38-1
Molecular Formula	C11H12F3N3O2
Molecular Weight	275.23 g/mol
Synonyms	1-[2-Nitro-4-(trifluoromethyl)phenyl]piperazine; 2-Nitro-4-(trifluoromethyl)phenylpiperazine; 4-(2-Nitro-4-trifluoromethylphenyl)piperazine; Piperazine, 1-[2-nitro-4-(trifluoromethyl)phenyl]-; N-(2-Nitro-4-trifluoromethylphenyl)piperazine
EINECS	Contact for details

Quality Control

Our n-[2-Nitro-4-(Trifluoromethyl)Phenyl]Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.