Description

Benzenepropanoyl Chloride, 4-Methyl- is a versatile and reactive organic intermediate, specifically an acyl chloride derivative of 4-methylhydrocinnamic acid. Its primary value lies in its role as a key building block for introducing the 4-methylphenylpropionyl moiety into more complex molecules, enabling the synthesis of pharmaceuticals, agrochemicals, and advanced materials. This compound is essential for research and development chemists, process engineers, and manufacturers in the fine chemical, pharmaceutical, and specialty chemical industries seeking to create novel compounds with specific biological or material properties.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for non-steroidal anti-inflammatory drugs (NSAIDs) and other therapeutic agents.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where the 4-methylphenylpropionyl group is a required structural component.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing advanced organic molecules used in display technologies and organic light-emitting diodes.
• Polymer & Resin Modification: Employed as a reactive monomer or cross-linking agent to introduce specific functional groups into polymer chains, enhancing material properties.
• Peptide & Protein Chemistry: Utilized as an acylating agent for modifying amino acids or protecting groups during complex peptide synthesis.
• Dye & Pigment Manufacturing: Acts as an intermediate in the production of specialized dyes and organic pigments.
• Flavor & Fragrance Ingredient Synthesis: Used to create aromatic esters and other compounds for the flavor and fragrance industry.
• Research & Development: A valuable reagent for academic and industrial R&D in organic synthesis and medicinal chemistry projects.

Basic Information

Item	Details
Product Name	Benzenepropanoyl Chloride, 4-Methyl-
CAS No.	58183-40-7
Molecular Formula	C10H11ClO
Molecular Weight	182.65 g/mol
Synonyms	4-Methylbenzenepropanoyl Chloride; 3-(4-Methylphenyl)propionyl Chloride; 4-Methylhydrocinnamoyl Chloride; β-(p-Tolyl)propionyl Chloride; 3-(p-Tolyl)propionyl Chloride; 4-Methylphenylpropionyl Chloride; p-Methylhydrocinnamoyl Chloride
EINECS	Contact for details

Quality Control

Our Benzenepropanoyl Chloride, 4-Methyl- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and reacts vigorously with water, strong bases, and alcohols. Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation from moisture and to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.