Description

2-Iodo-3-Methylpyrazine is a halogenated heterocyclic building block of significant importance in advanced organic synthesis. This compound serves as a versatile intermediate for the construction of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily utilized by research chemists and process development scientists for applications in medicinal chemistry, material science, and the synthesis of fine chemicals. Its specific reactivity profile makes it a valuable reagent for cross-coupling reactions and functional group transformations.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for the development of organic electronic materials, ligands for catalysis, and specialty polymers.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed reactions such as Suzuki, Stille, and Negishi couplings for carbon-carbon bond formation.
• Medicinal Chemistry & Drug Discovery: Employed in lead optimization and structure-activity relationship (SAR) studies to introduce iodine for halogen bonding or as a synthetic handle.
• Fine Chemical Production: Used in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	2-Iodo-3-Methylpyrazine
CAS No.	58139-08-5
Molecular Formula	C5H5IN2
Molecular Weight	220.01 g/mol
Synonyms	3-Methyl-2-iodopyrazine; 2-Iodo-3-methylpyrazine; Iodo-3-methylpyrazine; Pyrazine, 2-iodo-3-methyl-; 58139-08-5; SCHEMBL11821079; DTXSID90664669; BDBM50388895
EINECS	Contact for details

Quality Control

Our 2-Iodo-3-Methylpyrazine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to cGMP principles and ISO-aligned processes guarantees a reliable supply of high-purity material for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.