Description

2,3-Diiodopyrazine is a high-purity halogenated heterocyclic compound, serving as a versatile and critical building block in advanced organic synthesis. Its value lies in the strategic placement of iodine atoms on the pyrazine ring, making it an excellent substrate for cross-coupling reactions and functional group transformations. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, and insecticides with specific modes of action.
• Material Science: Used in the development of organic semiconductors, ligands for metal-organic frameworks (MOFs), and specialty polymers.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Sonogashira couplings to introduce complex pyrazine-based structures.
• Chemical Research: Serves as a standard reagent in methodological development and heterocyclic chemistry research within academic and industrial R&D labs.
• Ligand Preparation: Used to synthesize bidentate or polydentate ligands for catalysis and coordination chemistry.

Basic Information

Product Name	2,3-Diiodopyrazine
CAS No.	58139-07-4
Molecular Formula	C4H2I2N2
Molecular Weight	331.88 g/mol
Synonyms	Pyrazine, 2,3-diiodo-; 2,3-Diiodo-1,4-diazine; 2,3-Diiodopyrazine; Diiodopyrazine; 1,4-Diazine, 2,3-diiodo-; 2,3-Diiodo-pyrazine; 58139-07-4 (CAS)
EINECS	Contact for details

Quality Control

Our 2,3-Diiodopyrazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, handling and packaging are performed under controlled lighting conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.