Description

2-Iodo-6-Methylpyrazine is a halogenated heterocyclic building block of significant importance in advanced organic synthesis. This compound serves as a versatile intermediate, enabling the introduction of the 2-iodo-6-methylpyrazine moiety into more complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require specific pyrazine-based scaffolds.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for studying biological mechanisms and target engagement.
• Custom Synthesis and Scale-up: Supplied for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects from milligram to kilogram scale.

Basic Information

Product Name	2-Iodo-6-Methylpyrazine
CAS No.	58139-06-3
Molecular Formula	C5H5IN2
Molecular Weight	220.01 g/mol
Synonyms	6-Methyl-2-iodopyrazine; 2-Iodo-6-methyl-1,4-diazine; 2-Iodo-6-methylpyrazine; Iodomethylpyrazine; Pyrazine, 2-iodo-6-methyl-; 6-Methylpyrazin-2-yl iodide
EINECS	Contact for details

Quality Control

Our 2-Iodo-6-Methylpyrazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, handling should be performed under subdued light or using amber glass containers for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.