Description

3-Bromoimidazo[1,2-A]Pyrazine is a high-purity brominated heterocyclic building block of significant importance in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical agents and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science Precursor: Serves as a starting material for the synthesis of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology Probe: Employed in medicinal chemistry to create molecular probes for studying enzyme function and biological pathways.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form new carbon-carbon bonds.
• Library Synthesis for Drug Discovery: Used in high-throughput and combinatorial chemistry to generate diverse compound libraries for screening.

Basic Information

Product Name	3-Bromoimidazo[1,2-A]Pyrazine
CAS No.	57948-41-1
Molecular Formula	C6H4BrN3
Molecular Weight	198.02 g/mol
Synonyms	3-Bromoimidazo[1,2-a]pyrazine; Imidazo[1,2-a]pyrazine, 3-bromo-; 3-Bromo-imidazo[1,2-a]pyrazine; 57948-41-1; 3-Bromoimidazo(1,2-a)pyrazine; 3-Bromo-1H-imidazo[1,2-a]pyrazine; SCHEMBL11826927; BRN 1217640
EINECS	Contact for details

Quality Control

Our 3-Bromoimidazo[1,2-A]Pyrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.