Description

4-Amino-Piperidine-4-Carboxylic Acid Ethyl Ester 2Hcl is a high-purity, pharmaceutically relevant piperidine derivative, serving as a critical chiral building block and intermediate in organic synthesis. Its value lies in its bifunctional structure, which provides both a protected amino group and an ester moiety, enabling its use in constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of various drug candidates, including central nervous system (CNS) agents, antiviral compounds, and enzyme inhibitors.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its piperidine scaffold.
• Peptidomimetics & Bioactive Molecule Design: The amino acid ester structure makes it a valuable precursor for creating peptide analogs and other biologically active molecules.
• Ligand & Catalyst Development: Employed in the preparation of chiral ligands for asymmetric catalysis and metal complexes.
• Academic & R&D Laboratories: Serves as a versatile starting material for methodological studies in organic and medicinal chemistry.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Item	Details
Product Name	4-Amino-Piperidine-4-Carboxylic Acid Ethyl Ester 2Hcl
CAS No.	57611-99-1
Molecular Formula	C8H18N2O2 • 2HCl
Molecular Weight	255.16 g/mol (Free base: 186.25)
Synonyms	4-Amino-4-carbethoxypiperidine dihydrochloride; Ethyl 4-aminoisonipecotate dihydrochloride; 4-Amino-4-(ethoxycarbonyl)piperidine dihydrochloride; 4-(Ethoxycarbonyl)-4-aminopiperidine dihydrochloride; 4-Aminopiperidine-4-carboxylic acid ethyl ester hydrochloride (2:1); 4-Amino-4-piperidinecarboxylic acid ethyl ester dihydrochloride; 4-Carbethoxy-4-aminopiperidine dihydrochloride; 1,2,3,6-Tetrahydro-4-pyridinecarboxylic acid, 4-amino-, ethyl ester, dihydrochloride
EINECS	Contact for details

Quality Control

Our 4-Amino-Piperidine-4-Carboxylic Acid Ethyl Ester 2Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We support compliance with cGMP, ISO, and other relevant quality frameworks for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (HPLC, Area %)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.