Description

(10S)-10,11-Dihydro-8-Chloro-10-[(3S)-3-(Methylethylamino)Pyrrolizino]Dibenzo[B,F]Thiepin is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial value for its role in the synthesis of active pharmaceutical ingredients (APIs) targeting the central nervous system. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in producing innovative therapeutic agents.

Application

• Key Intermediate in CNS Drug Synthesis: Serves as a critical building block for the development of novel antipsychotic and neuroleptic pharmaceutical compounds.
• Pharmaceutical Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the creation of new chemical entities.
• Process Chemistry & Scale-Up: Employed in optimizing synthetic routes and scaling up production for clinical trial material and commercial API manufacturing.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and impurity profiling.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.

Basic Information

Product Name	(10S)-10,11-Dihydro-8-Chloro-10-[(3S)-3-(Methylethylamino)Pyrrolizino]Dibenzo[B,F]Thiepin
CAS No.	57602-85-4
Molecular Formula	C22H24ClN3S
Molecular Weight	397.96 g/mol
Synonyms	8-Chloro-10,11-dihydro-10-[(3S)-3-(isopropylamino)pyrrolidin-1-yl]dibenzo[b,f]thiepin; (S)-8-Chloro-10,11-dihydro-10-(3-(isopropylamino)pyrrolidin-1-yl)dibenzo[b,f]thiepin; Zotepine Impurity; Zotepine Related Compound; Zotepine Intermediate; Dibenzo[b,f]thiepin, 8-chloro-10,11-dihydro-10-[(3S)-3-[(1-methylethyl)amino]-1-pyrrolidinyl]-; 57602-85-4
EINECS	Contact for details

Quality Control

Our (10S)-10,11-Dihydro-8-Chloro-10-[(3S)-3-(Methylethylamino)Pyrrolizino]Dibenzo[B,F]Thiepin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and hygroscopic (moisture-sensitive); ensure containers are kept sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.