Description

Ibuprofen Lysine is a water-soluble lysine salt derivative of the widely used non-steroidal anti-inflammatory drug (NSAID) ibuprofen. This enhanced formulation offers significantly improved solubility and dissolution rate compared to the free acid, leading to faster absorption and onset of action. It is primarily utilized in the pharmaceutical industry for the development of advanced analgesic and anti-inflammatory formulations, including fast-acting tablets, effervescent preparations, and injectable solutions. The compound is valued for its ability to provide rapid pain relief, making it a key ingredient in products targeting acute pain management.

Application

• Pharmaceutical Analgesics: Primary active ingredient in fast-dissolving and effervescent tablets for rapid relief of mild to moderate pain, such as headaches, dental pain, and dysmenorrhea.
• Anti-inflammatory Medications: Used in formulations designed to reduce inflammation and associated symptoms in conditions like arthritis, soft tissue injuries, and post-operative care.
• Pediatric & Geriatric Formulations: Ideal for age-appropriate dosage forms due to its improved solubility, palatability, and ease of administration in liquid or dispersible formats.
• Injectable Solutions: Serves as a key component in parenteral formulations where rapid systemic delivery and high bioavailability are required in clinical settings.
• Veterinary Pharmaceuticals: Incorporated into veterinary medicines for the management of pain and inflammation in companion and livestock animals.
• Research & Development: Used as a reference standard and active pharmaceutical ingredient (API) in preclinical and clinical research for developing new NSAID-based therapies.

Basic Information

Product Name	Ibuprofen Lysine
CAS No.	57469-77-9
Molecular Formula	C19H32N2O3
Molecular Weight	336.47 g/mol
Synonyms	Ibuprofen Lysinate; Lysine Ibuprofen; (S)-2-(4-Isobutylphenyl)propanoic acid compound with (2S)-2,6-diaminohexanoic acid (1:1); DL-Lysine ibuprofen; Ibuprofen L-lysine salt; Ibuprofen lysine salt; Arginine Ibuprofen (related salt); Spedifen (brand name reference)
EINECS	Contact for details

Quality Control

Our Ibuprofen Lysine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. We provide Certificates of Analysis (COA) detailing key parameters such as assay, related substances, residual solvents, and microbiological quality. While typically produced to meet in-house specifications, production can be aligned with relevant pharmacopoeial standards (e.g., USP, EP) based on customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 0.5% Any single impurity ≤ 0.1%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 10 ppm
pH (1% solution)	6.0 - 8.0
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.