Description

Methylergonovine Maleate Salt CAS NO 57432-61-8 is a synthetic ergot alkaloid derivative, specifically the maleate salt form of methylergonovine. This compound is a critical active pharmaceutical ingredient (API) valued for its potent uterotonic properties. It is primarily required by pharmaceutical manufacturers and research institutions for the formulation of medications used in obstetric and gynecological care.

Application

• Pharmaceutical API: Primary use as the active ingredient in injectable and oral formulations for the prevention and treatment of postpartum hemorrhage (PPH).
• Research Chemical: Used in biochemical and pharmacological research to study its mechanism of action as a serotonin and α-adrenergic receptor agonist.
• Reference Standard: Serves as a high-purity analytical standard in quality control laboratories for drug testing and method validation.
• Veterinary Medicine: Potential application in veterinary obstetrics for managing postpartum bleeding in animals.

Basic Information

Product Name	Methylergonovine Maleate Salt
CAS No.	57432-61-8
Molecular Formula	C₂₀H₂₅N₃O₂ • C₄H₄O₄
Molecular Weight	455.5 g/mol
Synonyms	Methylergometrine Maleate; Methylergobasine Maleate; (+)-Methylergonovine Maleate; 9,10-Didehydro-N-[(S)-1-(hydroxymethyl)propyl]-6-methylergoline-8β-carboxamide Maleate; Methergine (brand name); Methylergobrevin Maleate; Methylergonovine Hydrogen Maleate; D-Lysergic Acid Butanolamide Maleate
EINECS	Contact for details

Quality Control

Our Methylergonovine Maleate Salt is manufactured and tested under strict quality management systems. We offer material suitable for pharmaceutical development, with testing typically including identification, assay, related substances, residual solvents, and specific tests for ergot alkaloids. Certificates of Analysis (COA) detailing compliance with in-house specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities: NMT 2.0% Any individual impurity: NMT 0.5%
Water (KF)	NMT 5.0%
Residue on Ignition	NMT 0.1%
Heavy Metals	NMT 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.