Description

4-Methoxy-4-Oxo-3-(Triphenylphosphoranylidene)-Butanoic Acid is a specialized Wittig-Horner reagent, a key building block in advanced organic synthesis. Its primary value lies in its ability to facilitate the efficient formation of α,β-unsaturated esters and related compounds under mild conditions. This high-purity intermediate is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Critical for the synthesis of complex drug molecules, particularly those containing α,β-unsaturated carbonyl moieties.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides requiring specific olefination steps.
• Material Science Research: Serves as a precursor for creating novel polymers and functional organic materials with tailored properties.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic chemistry and the construction of complex natural product analogs.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where precise olefination is required.

Basic Information

Product Name	4-Methoxy-4-Oxo-3-(Triphenylphosphoranylidene)-Butanoic Acid
CAS No.	57367-54-1
Molecular Formula	C23H21O4P
Molecular Weight	392.38 g/mol
Synonyms	3-(Triphenylphosphoranylidene)-4-methoxy-4-oxobutanoic acid; (Carboxymethylene)triphenylphosphorane methyl ester; Methyl (triphenylphosphoranylidene)acetate-2-carboxylic acid; Wittig-Horner reagent for α,β-unsaturated esters; Methyl 2-(triphenylphosphoranylidene)succinate; Phosphonium, (2-methoxy-2-oxoethylidene)triphenyl-, inner salt; Butanoic acid, 4-methoxy-4-oxo-3-(triphenylphosphoranylidene)-
EINECS	Contact for details

Quality Control

Our 4-Methoxy-4-Oxo-3-(Triphenylphosphoranylidene)-Butanoic Acid is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and process chemistry. Each lot is analyzed using advanced techniques including HPLC, NMR, and titration to confirm identity and potency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect reactivity and stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystals
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.