Description

3β-(Trimethylsiloxy)Pregna-5,16-Dien-20-One o-Benzyl Oxime is a high-purity, advanced steroid intermediate characterized by its specific functionalization. This compound is critical for the synthesis of complex pharmaceutical agents, offering a precise chemical handle for further derivatization. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of steroidal drugs and novel therapeutic compounds.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of active pharmaceutical ingredients (APIs) with steroidal backbones.
• Steroid Hormone Research: Used in academic and industrial R&D for studying structure-activity relationships and developing new hormonal therapies.
• Process Chemistry: Serves as a critical precursor in optimizing scalable manufacturing routes for complex steroid molecules.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Biochemical Tool Compound: Utilized in pharmacological studies to investigate steroid receptor interactions and metabolic pathways.

Basic Information

Product Name	3β-(Trimethylsiloxy)Pregna-5,16-Dien-20-One o-Benzyl Oxime
CAS No.	57325-71-0
Molecular Formula	C32H47NO2Si
Molecular Weight	505.81 g/mol
Synonyms	3β-(Trimethylsilyloxy)pregna-5,16-dien-20-one O-benzyloxime; (3β)-3-[(Trimethylsilyl)oxy]pregna-5,16-dien-20-one O-(phenylmethyl)oxime; Pregna-5,16-dien-20-one, 3-[(trimethylsilyl)oxy]-, O-(phenylmethyl)oxime, (3β)-; 3β-Hydroxypregna-5,16-dien-20-one 3-trimethylsilyl ether O-benzyl oxime; 3-TMS Ether of Pregna-5,16-dien-20-one O-benzyl oxime; 57325-71-0; 3β-TMS-Pregna-5,16-dien-20-one OBn-oxime
EINECS	Contact for details

Quality Control

Our 3β-(Trimethylsiloxy)Pregna-5,16-Dien-20-One o-Benzyl Oxime is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.