Description

8-(Carboxyacetyl)-3-Methyl-3,8-Diazabicyclo[3.2.1]Octane is a high-purity, advanced pharmaceutical intermediate featuring a unique diazabicyclooctane core structure. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological and cardiovascular pathways. It is essential for research and development chemists and manufacturers in the pharmaceutical and fine chemical industries who require reliable, high-quality intermediates for complex multi-step syntheses.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those with complex polycyclic architectures.
• Neurological Drug Development: Used in the research and production of compounds targeting central nervous system (CNS) receptors.
• Cardiovascular API Synthesis: Serves as a building block for active ingredients in cardiovascular therapeutics.
• Ligand and Catalyst Development: Utilized in the creation of specialized ligands and catalysts for asymmetric synthesis.
• Academic and Industrial R&D: Employed in medicinal chemistry research for structure-activity relationship (SAR) studies and lead optimization.
• Fine Chemical Production: Integral to the multi-step synthesis of high-value, complex organic molecules.

Basic Information

Product Name	8-(Carboxyacetyl)-3-Methyl-3,8-Diazabicyclo[3.2.1]Octane
CAS No.	57269-36-0
Molecular Formula	C11H18N2O3
Molecular Weight	226.27 g/mol
Synonyms	3-Methyl-8-(2-carboxyacetyl)-3,8-diazabicyclo[3.2.1]octane; 8-(Carboxyacetyl)-3-methyl-3,8-diazabicyclo[3.2.1]octane; 3,8-Diazabicyclo[3.2.1]octane-8-acetic acid, 3-methyl-, α-carboxy-; Tropane-3-carboxylic acid, 8-(carboxymethyl)-, methyl ester (related structure); 8-(2-Carboxyacetyl)-3-methyl-3,8-diazabicyclo[3.2.1]octane; DABCO derivative 57269-36-0
EINECS	Contact for details

Quality Control

Our 8-(Carboxyacetyl)-3-Methyl-3,8-Diazabicyclo[3.2.1]Octane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.