Description

Biliverdin Ix Alpha Dimethyl Ester is a chemically modified derivative of biliverdin, a key intermediate in the heme catabolic pathway. This dimethyl ester form offers enhanced stability and lipophilicity, making it a valuable biochemical reagent and research standard. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical development, and analytical chemistry sectors for studying bile pigment metabolism, antioxidant mechanisms, and as a reference material.

Application

• Biochemical Research: Used as a critical standard and reagent in studies of heme degradation, bilirubin biosynthesis, and related metabolic pathways.
• Pharmaceutical Intermediates: Serves as a potential starting material or intermediate in the synthesis of novel therapeutic agents and diagnostic probes.
• Antioxidant Studies: Employed in vitro to investigate the antioxidant and radical-scavenging properties of bile pigments and their derivatives.
• Analytical Reference Standard: Essential for the calibration of analytical instruments (HPLC, LC-MS) and for method development in pigment analysis.
• Cell Biology & Signaling: Applied in research exploring the potential biological roles of biliverdin derivatives in cellular signaling and cytoprotection.
• Dye & Pigment Chemistry: Investigated as a precursor for developing natural colorants or photosensitive compounds.

Basic Information

Product Name	Biliverdin Ix Alpha Dimethyl Ester
CAS No.	57158-62-0
Molecular Formula	C₃₅H₃₈N₄O₆
Molecular Weight	610.71 g/mol
Synonyms	Biliverdin dimethyl ester; Biliverdin IXα dimethyl ester; 3,18-Diethenyl-1,19,22,24-tetrahydro-2,7,13,17-tetramethyl-1,19-dioxo-21,24-methano-21H-biline-8,12-dipropanoic acid dimethyl ester; 21,24-Dihydro-21,24-methanobilin-1,19-dione, 3,18-diethenyl-1,19,22,24-tetrahydro-2,7,13,17-tetramethyl-8,12-dipropanoic acid dimethyl ester; Biliverdin-IXα-DME; (3Z)-3-[(2Z)-2-[(3Z)-3-(2-Carboxyethyl)-5-[(3-ethyl-4-methyl-5-oxo-1,2-dihydro-2-pyrrolylidene)methyl]-4-methyl-1H-pyrrol-2-ylidene]ethylidene]-5-[(3-ethyl-4-methyl-5-oxo-1,2-dihydro-2-pyrrolylidene)methyl]-4-methyl-1H-pyrrole-2-propanoic acid dimethyl ester
EINECS	Contact for details

Quality Control

Our Biliverdin Ix Alpha Dimethyl Ester is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic identification (UV-Vis, IR), to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Dark green to blue-green crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (UV-Vis)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0 %
Solubility	Soluble in DMSO, DMF; sparingly soluble in chloroform, methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.