Description

Proglumetacin Maleate is a non-steroidal anti-inflammatory drug (NSAID) prodrug, combining the anti-inflammatory agent proglumetacin with maleic acid. This compound is valued for its targeted delivery and enhanced stability profile, offering a strategic advantage in pharmaceutical development. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the formulation of advanced analgesic and anti-inflammatory therapies.

Application

• Pharmaceutical Intermediate: Serves as a key active pharmaceutical ingredient (API) or precursor in the synthesis of finished dosage forms.
• Anti-inflammatory Drug Research: Used in preclinical and clinical research for developing new NSAID formulations with improved efficacy and safety margins.
• Analgesic Development: A critical component in R&D projects focused on creating novel pain management solutions.
• Prodrug Studies: Employed in pharmacokinetic and pharmacodynamic studies to understand and enhance drug delivery and bioavailability.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Proglumetacin Maleate
CAS No.	57132-53-3
Molecular Formula	C23H27ClN2O6 • C4H4O4
Molecular Weight	599.0 g/mol
Synonyms	Proglumetacin Maleate; 1-(p-Chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid 2-(di-n-propylamino)ethyl ester maleate; Proglumetacin Hydrogen Maleate; Proglumetasin Maleate; CR 604; NSC 332488; Proglumetacin (Maleate)
EINECS	Contact for details

Quality Control

Our Proglumetacin Maleate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC and other validated methods, to ensure it meets stringent specifications for pharmaceutical research and development. Certificates of Analysis (COA) are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.