Description

(3S,3Aα,4Aα,7Aβ,9Aα)-Dodecahydro-5α,7α-Dihydroxy-3,5-Dimethyl-8-Methyleneazuleno[6,5-B]Furan-2-One is a high-purity, complex sesquiterpene lactone derivative with significant potential in advanced organic synthesis and pharmaceutical research. Its intricate stereochemistry and functional groups make it a valuable chiral building block and intermediate for developing novel bioactive compounds. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to explore new molecular entities and synthetic pathways.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of potential drug candidates, particularly for anti-inflammatory or anticancer agents.
• Advanced Organic Synthesis: Used as a sophisticated building block for constructing complex natural product analogs and novel heterocyclic compounds.
• Agrochemical Research: Investigated as an intermediate for developing new plant growth regulators or bioactive agrochemicals with specific stereochemical requirements.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes to study biological pathways and enzyme interactions.
• Academic & Industrial R&D: A critical material for methodological development in stereoselective synthesis and catalysis research.
• Fine Chemical Production: Employed in the multi-step synthesis of high-value specialty chemicals and flavors/fragrances.

Basic Information

Product Name	(3S,3Aα,4Aα,7Aβ,9Aα)-Dodecahydro-5α,7α-Dihydroxy-3,5-Dimethyl-8-Methyleneazuleno[6,5-B]Furan-2-One
CAS No.	57095-90-6
Molecular Formula	C15H22O4
Molecular Weight	266.33 g/mol
Synonyms	5α,7α-Dihydroxy-3,5-dimethyldodecahydro-8-methyleneazuleno[6,5-b]furan-2(3H)-one; Dihydrocostunolide derivative; 8-Methyleneazuleno[6,5-b]furan-2-one, dodecahydro-5,7-dihydroxy-3,5-dimethyl-, (3S,3aα,4aα,7aβ,9aα)-; Sesquiterpene lactone intermediate; Costunolide analog; Guaianolide derivative
EINECS	Contact for details

Quality Control

Every batch of our (3S,3Aα,4Aα,7Aβ,9Aα)-Dodecahydro-5α,7α-Dihydroxy-3,5-Dimethyl-8-Methyleneazuleno[6,5-B]Furan-2-One is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency suitable for research and development applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.