Description

Denbufylline is a high-purity pharmaceutical intermediate and research chemical with significant pharmacological interest. This compound is valued for its role in the development and synthesis of novel therapeutic agents targeting specific cellular pathways. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic research institutions engaged in drug discovery and biochemical studies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced active pharmaceutical ingredients (APIs) with targeted biological activity.
• Biochemical Research: Used as a reference standard or tool compound in pharmacological studies to investigate specific enzyme interactions and cellular mechanisms.
• Drug Discovery & Development: Serves as a core structure for medicinal chemistry programs aimed at creating new drug candidates for various therapeutic areas.
• Academic & Clinical Research: Employed in university and hospital laboratories for preclinical studies to understand its pharmacokinetic and pharmacodynamic properties.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up synthesis under cGMP conditions for clinical trial material production.

Basic Information

Product Name	Denbufylline
CAS No.	57076-71-8
Molecular Formula	C19H25N5O3
Molecular Weight	371.44 g/mol
Synonyms	1,3-Diethyl-8-(1,3-dioxolan-2-ylmethyl)-7-methyl-3,7-dihydro-1H-purine-2,6-dione; BRL 30892; Denbufyllinum; 1,3-Diethyl-8-(1,3-dioxolan-2-ylmethyl)-7-methylxanthine; 1H-Purine-2,6-dione, 3,7-dihydro-1,3-diethyl-8-[(1,3-dioxolan-2-yl)methyl]-7-methyl-
EINECS	Contact for details

Quality Control

Our Denbufylline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data to support its use in regulated research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch upon request, aligning with industry best practices for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.