Description

1-[3-(4-Hydroxy-3,5-Dimethoxyphenyl)-1-Oxo-2-Propenyl]-4-[(1-Pyrrolidinyl)Carbonylmethyl]Piperazine is a complex synthetic intermediate featuring a piperazine core functionalized with a pyrrolidine carbonylmethyl group and a chalcone-like moiety. This compound is valued for its structural complexity, which makes it a versatile building block in advanced organic synthesis and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for the development of novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting neurological or metabolic pathways.
• Chemical Research & Development: Used as a sophisticated building block for constructing complex molecular architectures in academic and industrial research labs.
• Ligand Synthesis: Potential use in the development of chelating agents or catalysts due to its nitrogen-rich piperazine and pyrrolidine groups.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, agrochemicals, and advanced materials.
• Bioconjugation Chemistry: The reactive carbonyl and phenolic groups can be utilized for linking molecules in bioconjugation and probe development.

Basic Information

Item	Details
Product Name	1-[3-(4-Hydroxy-3,5-Dimethoxyphenyl)-1-Oxo-2-Propenyl]-4-[(1-Pyrrolidinyl)Carbonylmethyl]Piperazine
CAS No.	57061-75-3
Molecular Formula	C21H29N3O5
Molecular Weight	403.47 g/mol
Synonyms	4-[(1-Pyrrolidinyl)Carbonylmethyl]-1-[3-(4-Hydroxy-3,5-Dimethoxyphenyl)-1-Oxo-2-Propenyl]Piperazine; 1-[3-(4-Hydroxy-3,5-dimethoxyphenyl)-1-oxo-2-propen-1-yl]-4-[(pyrrolidin-1-yl)acetyl]piperazine; 1-[3-(4-Hydroxy-3,5-dimethoxyphenyl)acryloyl]-4-(2-pyrrolidin-1-yl-2-oxoethyl)piperazine; 57061-75-3; UNII-2Q2T2C9W6H; 2Q2T2C9W6H; AOB67717; HY-113464; ZINC000003869777; 4-(2-Oxo-2-pyrrolidin-1-ylethyl)-1-[3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoyl]piperazine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, residual solvents, and related substances are available upon request. We adhere to cGMP principles where applicable to support our clients in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.