Description

1-(2-Chloroethyl)-4-[3-(Trifluoromethyl)Phenyl]Piperazine Dihydrochloride is a high-purity, synthetically versatile piperazine derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmacological research intermediate and a key building block for the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D organizations and fine chemical manufacturers engaged in the synthesis of complex molecules for therapeutic applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Chemical Research & Development: Used as a versatile building block for constructing complex piperazine-based molecular scaffolds in medicinal chemistry.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in the multi-step synthesis of potential APIs, leveraging its reactive chloroethyl and piperazine functional groups.
• Biochemical Tool Compound: Serves as a research chemical for studying receptor-ligand interactions and biological pathways in academic and industrial laboratories.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals requiring a high degree of structural specificity and purity.

Basic Information

Product Name	1-(2-Chloroethyl)-4-[3-(Trifluoromethyl)Phenyl]Piperazine Dihydrochloride
CAS No.	57061-71-9
Molecular Formula	C13H17ClF3N2•2HCl
Molecular Weight	367.66 g/mol
Synonyms	1-(2-Chloroethyl)-4-(3-trifluoromethylphenyl)piperazine dihydrochloride; 4-(3-Trifluoromethylphenyl)-1-(2-chloroethyl)piperazine dihydrochloride; N-(2-Chloroethyl)-N'-(3-trifluoromethylphenyl)piperazine dihydrochloride; 1-(2-Chloroethyl)-4-(α,α,α-trifluoro-m-tolyl)piperazine dihydrochloride; TFMPP derivative dihydrochloride; m-CF3-PP dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-(2-Chloroethyl)-4-[3-(Trifluoromethyl)Phenyl]Piperazine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your research and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.