Description

Isonixin is a high-purity, non-steroidal anti-inflammatory drug (NSAID) intermediate of significant commercial and pharmaceutical importance. Its primary value lies in its role as a critical building block for the synthesis of potent anti-inflammatory and analgesic agents, ensuring the quality and efficacy of the final active pharmaceutical ingredients (APIs). This compound is essential for manufacturers and R&D facilities in the global pharmaceutical, fine chemical, and contract research organization (CRO) sectors seeking reliable, high-grade raw materials for advanced drug development and production.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel non-steroidal anti-inflammatory drugs (NSAIDs) and related analgesic compounds.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core scaffold for research and development of new therapeutic agents targeting inflammation and pain.
• Fine Chemical Synthesis: Used in multi-step organic synthesis for creating complex molecules with specific biological activities.
• Contract Manufacturing: Supplied to CMOs (Contract Manufacturing Organizations) for the production of branded or generic pharmaceutical formulations.
• Biochemical Research: Utilized in academic and industrial laboratories for pharmacological studies and mechanism of action research.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical manufacturing.

Basic Information

Product Name	Isonixin
CAS No.	57021-61-1
Molecular Formula	C14H12N2O3
Molecular Weight	256.26 g/mol
Synonyms	4-Isobutyl-2-methyl-1,8-naphthyridin-1(2H)-one; 1,2-Dihydro-4-isobutyl-2-methyl-1,8-naphthyridin-1-one; Isonixin; Isoxicam Impurity; Isoxicam Related Compound; 1,8-Naphthyridin-1(2H)-one, 4-isobutyl-2-methyl-; Isoxicam Intermediate
EINECS	Contact for details

Quality Control

Our Isonixin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for pharmaceutical applications. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet stringent in-house specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment, and we support compliance with cGMP, ICH Q7, and other relevant regulatory guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.