Description

1-(Bromomethyl)Cyclopropanecarboxylic Acid is a versatile bifunctional building block featuring both a reactive bromomethyl group and a carboxylic acid moiety. This compound is valued for its ability to introduce the constrained cyclopropane ring system into target molecules, a key structural motif in medicinal chemistry and advanced materials. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for constructing cyclopropane-containing drug candidates, including protease inhibitors, receptor modulators, and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the cyclopropane ring enhances biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of monomers and polymers with unique thermal or mechanical properties derived from the strained ring system.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or affinity probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring precise introduction of the (bromomethyl)cyclopropyl fragment.

Basic Information

Product Name	1-(Bromomethyl)Cyclopropanecarboxylic Acid
CAS No.	56834-40-3
Molecular Formula	C5H7BrO2
Molecular Weight	179.01 g/mol
Synonyms	Cyclopropanecarboxylic acid, 1-(bromomethyl)-; 1-(Bromomethyl)cyclopropanecarboxylic acid; (Bromomethyl)cyclopropanecarboxylic acid; 1-Bromomethyl-1-cyclopropanecarboxylic acid; (1-Bromomethylcyclopropyl)carboxylic acid; NSC 339063; 1-Carboxycyclopropylmethyl bromide
EINECS	Contact for details

Quality Control

Our 1-(Bromomethyl)Cyclopropanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.