Description

1,2-Di9-trans-Hexa-Decenoyl-Sn-Glycero-3-Phosphocholine is a high-purity, synthetic phospholipid specifically designed for advanced research and formulation applications. This compound is a critical component for creating model lipid membranes and liposomal delivery systems due to its defined acyl chain structure. It is essential for researchers and product developers in the pharmaceutical, biotechnology, and advanced material science sectors who require precise and reliable lipid components.

Application

• Liposome and Lipid Nanoparticle (LNP) Formulation: A key structural phospholipid for constructing drug delivery vehicles for mRNA, siRNA, and small molecule therapeutics.
• Biomembrane Research: Used to create synthetic lipid bilayers and vesicles for studying membrane biophysics, protein-lipid interactions, and cellular processes.
• Drug Discovery & Development: Serves as an excipient in preclinical studies for enhancing the solubility and bioavailability of hydrophobic active pharmaceutical ingredients (APIs).
• Diagnostic Reagents: Incorporated into assay kits and diagnostic tools where controlled membrane environments are required.
• Cosmetic & Dermal Formulations: Used in high-end cosmetic products as a biomimetic ingredient to improve skin barrier function and delivery of active compounds.
• Biophysical Studies: Essential for techniques like NMR, fluorescence spectroscopy, and calorimetry to investigate lipid packing, phase behavior, and dynamics.

Basic Information

Product Name	1,2-Di9-trans-Hexa-Decenoyl-Sn-Glycero-3-Phosphocholine
CAS No.	56816-00-3
Molecular Formula	C44H82NO8P
Molecular Weight	784.10 g/mol
Synonyms	1,2-Di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine; DOPE (common abbreviation); 1,2-Dioleoyl-sn-glycero-3-phosphocholine (related isomer); 1,2-Di-(cis-9-octadecenoyl)-sn-glycero-3-phosphocholine; Phosphatidylcholine, 1,2-di-(9Z-octadecenoyl)-, (R)-; (R)-2,3-Bis((9Z)-octadec-9-enoyloxy)propyl 2-(trimethylammonio)ethyl phosphate; 18:1 (δ9-Cis) PC (lipid number notation); Dioleoylphosphatidylcholine
EINECS	Contact for details

Quality Control

Our 1,2-Di9-trans-Hexa-Decenoyl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and GMP-guided development. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines for lipid synthesis and purification to meet the exacting standards of the life sciences sector.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. This product is hygroscopic (moisture-sensitive) and easily oxidized; allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR / NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Solubility	Soluble in chloroform, ethanol; insoluble in water
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm
Water Content (KF)	< 1.0%
Peroxide Value	< 1.0 meq/kg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.