Description

Troxerutin is a semi-synthetic derivative of the natural bioflavonoid rutin, known for its potent venotonic and capillary-protective properties. This compound is highly valued for its ability to improve microcirculation and reduce vascular permeability and fragility. It is a critical active pharmaceutical ingredient (API) and nutraceutical component for manufacturers in the pharmaceutical, dietary supplement, and cosmetic industries seeking to develop products for vascular health.

Application

• Pharmaceutical Formulations: Primary API in prescription and OTC medications for chronic venous insufficiency, hemorrhoids, varicose veins, and post-surgical edema.
• Dietary Supplements: Key ingredient in capsules, tablets, and powders targeting circulatory support, leg heaviness, and antioxidant protection.
• Cosmetic & Skincare Products: Used in creams, serums, and gels for its anti-inflammatory and capillary-strengthening effects, helping to reduce dark circles, puffiness, and redness.
• Veterinary Medicine: Incorporated into animal health products for similar circulatory and anti-edema applications.
• Research & Development: Serves as a reference standard and key intermediate in biochemical research focused on vascular biology and flavonoid activity.

Basic Information

Product Name	Troxerutin
CAS No.	56764-99-9
Molecular Formula	C33H42O19
Molecular Weight	742.68 g/mol
Synonyms	Trihydroxyethylrutin; Vitamin P4; Rutin trihydroxyethyl ether; (2R,3R,4S,5S,6R)-2-[[(2R,3R,4S,5S,6R)-4,5-Dihydroxy-2-(hydroxymethyl)-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-2-oxanyl]oxy]oxan-3-yl]oxy]-6-[5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-4-oxochromen-3-yl]oxyoxane-3,4,5-triol; Troxerutine; Paroven; Venoruton; Zyroven
EINECS	260-363-3

Quality Control

Our Troxerutin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for assay and purity, to ensure it meets high-grade specifications suitable for pharmaceutical and nutraceutical use. Certificates of Analysis (COA) are provided with every shipment, confirming compliance with relevant in-house standards and customer-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Yellow to yellow-brown powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 3.0%
Microbiological Control	Total Plate Count ≤ 1000 cfu/g; Yeast & Mold ≤ 100 cfu/g; Absence of E. coli, Salmonella

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.