Description

1,2-Dimyristoleoyl-Sn-Glycero-3-Phosphocholine is a high-purity, synthetic phospholipid featuring dimyristoleoyl (C14:1) fatty acid chains. This compound is a critical component for constructing advanced lipid-based delivery systems and biomimetic membranes due to its defined structure and unsaturated hydrocarbon tails. It is essential for researchers and formulators in the pharmaceutical, biotechnology, and nutraceutical industries developing liposomes, lipid nanoparticles (LNPs), and other sophisticated drug delivery platforms.

Application

• Liposome & Lipid Nanoparticle (LNP) Formulation: A key structural lipid for creating stable, fusogenic vesicles for mRNA, siRNA, and small molecule drug delivery.
• Biomimetic Membrane Research: Used in model membrane systems (e.g., supported lipid bilayers, vesicles) to study membrane fluidity, protein-lipid interactions, and permeability.
• Drug Delivery Excipient: Serves as a functional excipient to enhance the encapsulation efficiency and bioavailability of poorly soluble active pharmaceutical ingredients (APIs).
• Cosmetic Actives Carrier: Employed in high-end cosmetic formulations to improve the skin penetration and stability of active compounds.
• Diagnostic Reagent Component: Utilized in the development of diagnostic assays and imaging agents that require specific membrane environments.
• Cell Culture & Biochemistry: Applied in specialized cell culture media supplements and as a substrate or effector in enzymatic studies involving phospholipases.

Basic Information

Product Name	1,2-Dimyristoleoyl-Sn-Glycero-3-Phosphocholine
CAS No.	56750-90-4
Molecular Formula	C36H68NO8P
Molecular Weight	673.90 g/mol
Synonyms	DMPC (14:1); 1,2-Di(cis-tetradec-9-enoyl)-sn-glycero-3-phosphocholine; PC(14:1/14:1); 1,2-Dimyristoleoylphosphatidylcholine; 1,2-Ditetradeca-9Z-enoyl-sn-glycero-3-phosphocholine; Dimyristoleoyl Phosphatidylcholine; Phosphatidylcholine(14:1); (2R)-2,3-Bis[[(9Z)-tetradec-9-enoyl]oxy]propyl 2-(trimethylazaniumyl)ethyl phosphate
EINECS	Contact for details

Quality Control

Our 1,2-Dimyristoleoyl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and cGMP-grade formulation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, fatty acid profile, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. For long-term storage, desiccate at -20°C. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white waxy solid or film
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Fatty Acid Composition (GC)	Myristoleic acid (C14:1) ≥ 95% of total fatty acids
Lyso-Phosphatidylcholine (HPLC)	≤ 1.0%
Solvent Residues (GC)	Meets ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.