Description

24-Hydroxyvitamin D3 is a key intermediate metabolite in the vitamin D endocrine system, playing a crucial role in calcium homeostasis and bone metabolism. This compound is essential for research and development in the pharmaceutical and nutraceutical industries, where precise biochemical pathways are studied. It is primarily utilized by manufacturers of active pharmaceutical ingredients (APIs), clinical research organizations, and developers of diagnostic assays.

Application

• Pharmaceutical Intermediate: Critical starting material or reference standard in the synthesis of advanced vitamin D analogs and metabolites for therapeutic applications.
• Biochemical Research: Used as a high-purity reference compound in studies investigating vitamin D metabolism, receptor binding, and gene regulation.
• Clinical Diagnostics: Serves as a calibrant or standard in the development and validation of LC-MS/MS and immunoassay kits for quantifying vitamin D status.
• Nutraceutical Development: Employed in research for formulating advanced dietary supplements targeting bone health and calcium absorption.
• Metabolite Standard: Essential for analytical method development and quality control in laboratories measuring 24,25-dihydroxyvitamin D3 and related metabolites.

Basic Information

Product Name	24-Hydroxyvitamin D3
CAS No.	56720-87-7
Molecular Formula	C₂₇H₄₄O₃
Molecular Weight	416.64 g/mol
Synonyms	24-Hydroxycholecalciferol; 24R-Hydroxyvitamin D3; 24-Hydroxy-D3; (5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-3β,24-diol; 24(OH)D3; 24,25-Dihydroxyvitamin D3 precursor
EINECS	Contact for details

Quality Control

Our 24-Hydroxyvitamin D3 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light). For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC, IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.