Description

(3As,6E,10Z)-3-Methylene-4α-(2-Methylbutanoyloxy)-5β-Acetoxy-6-Formyl-10-(Hydroxymethyl)-2,3,3Aβ,4,5,8,9,11Aα-Octahydrocyclodeca[B]Furan-2-One is a complex, high-purity sesquiterpene lactone derivative with a defined stereochemistry. This compound serves as a critical advanced intermediate for the synthesis of novel bioactive molecules and complex natural product analogs. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents and conducting structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel sesquiterpene-based drug candidates with potential anti-inflammatory or anticancer activity.
• Medicinal Chemistry Research: Used in lead optimization and SAR studies to explore new chemical space and biological targets.
• Natural Product Synthesis: Serves as a sophisticated precursor in the total or semi-synthesis of complex natural products and their analogs.
• Biochemical Probe Development: Employed in the creation of specialized probes for studying biological pathways and enzyme interactions.
• Fine Chemical Production: An essential intermediate for manufacturers producing high-value, low-volume specialty chemicals for advanced applications.
• Academic Research: Used in university and institutional labs for cutting-edge organic synthesis and chemical methodology development.

Basic Information

Product Name	(3As,6E,10Z)-3-Methylene-4α-(2-Methylbutanoyloxy)-5β-Acetoxy-6-Formyl-10-(Hydroxymethyl)-2,3,3Aβ,4,5,8,9,11Aα-Octahydrocyclodeca[B]Furan-2-One
CAS No.	56679-19-7
Molecular Formula	C22H30O7
Molecular Weight	406.47 g/mol
Synonyms	3-Methylene-4α-(2-methylbutanoyloxy)-5β-acetoxy-6-formyl-10-(hydroxymethyl)-2,3,3aβ,4,5,8,9,11aα-octahydrocyclodeca[b]furan-2-one; 4α-(2-Methylbutyryloxy)-5β-acetoxy-3-methylene-6-formyl-10-hydroxymethyl-2,3,3aβ,4,5,8,9,11aα-octahydrocyclodeca[b]furan-2-one; A sesquiterpene lactone derivative; Cyclodeca[b]furan-2-one derivative; Advanced pharmaceutical intermediate.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems to ensure batch-to-batch consistency and high purity. Identity and purity are confirmed through a combination of analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.