Description

1-(4-Hydroxyphenyl)Piperazine is a versatile aromatic piperazine derivative, a key organic intermediate prized for its dual functional groups that enable diverse chemical modifications. This compound is essential for synthesizing high-value specialty chemicals and active pharmaceutical ingredients (APIs) requiring a phenolic piperazine scaffold. It is primarily needed by research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in creating novel compounds for therapeutic and material science applications.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of various drug candidates, particularly those targeting neurological and cardiovascular systems.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its structural motif for bioactivity.
• Dye and Pigment Manufacturing: Serves as a precursor in the production of specialized dyes and colorants due to its aromatic and amine functionalities.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers and resins.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Ligand Synthesis: Utilized in creating complexing agents and ligands for catalysis and metal ion sequestration.

Basic Information

Product Name	1-(4-Hydroxyphenyl)Piperazine
CAS No.	56621-48-8
Molecular Formula	C10H14N2O
Molecular Weight	178.23 g/mol
Synonyms	4-(1-Piperazinyl)phenol; 4-Piperazin-1-ylphenol; 1-(4-Hydroxyphenyl)piperazine; 4-Hydroxyphenylpiperazine; 4-(Piperazin-1-yl)phenol; N-(4-Hydroxyphenyl)piperazine; p-Hydroxyphenylpiperazine
EINECS	Contact for details

Quality Control

Our 1-(4-Hydroxyphenyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. For long-term storage, consider using an inert atmosphere to mitigate potential oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.