Description

1-Octadecanoyl-2-[cis-9-Octadecenoyl]-Sn-Glycero-3-Phosphocholine is a high-purity, synthetic phospholipid with a defined fatty acid composition. This compound is critical for research and development in advanced drug delivery systems, particularly for creating stable and biocompatible liposomal formulations. It is primarily utilized by pharmaceutical researchers, formulation scientists, and manufacturers in the life sciences sector for applications in targeted therapy and membrane biophysics studies.

Application

• Liposome & Lipid Nanoparticle (LNP) Formulation: A key structural component for creating stable, uniform liposomes used in drug delivery, mRNA vaccines, and diagnostic imaging agents.
• Biomembrane & Model Membrane Research: Used to construct defined lipid bilayers for studying membrane fluidity, protein-lipid interactions, and cell signaling mechanisms.
• Pharmaceutical Excipient: Serves as a functional excipient in advanced parenteral formulations to enhance drug solubility, stability, and targeted release profiles.
• Biochemical & Cell Culture Reagents: Employed in the preparation of specialized media supplements and reagents for cell biology and biochemistry experiments.
• Cosmetic & Dermal Delivery Systems: Incorporated into high-end cosmetic formulations for its emulsifying properties and ability to improve skin penetration of active ingredients.
• Reference Standard & Analytical Chemistry: Used as a certified reference material (CRM) for quality control and analytical method development in pharmaceutical analysis.

Basic Information

Product Name	1-Octadecanoyl-2-[cis-9-Octadecenoyl]-Sn-Glycero-3-Phosphocholine
CAS No.	56421-10-4
Molecular Formula	C44H86NO8P
Molecular Weight	788.13 g/mol
Synonyms	1-Stearoyl-2-Oleoyl-sn-Glycero-3-Phosphocholine; SOPC; 18:0-18:1 PC; Phosphatidylcholine, 1-stearoyl-2-oleoyl-; 1-Octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine; (2R)-2,3-Bis(octadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate; 1-Stearoyl-2-oleoylphosphatidylcholine; POPC analog (saturated variant)
EINECS	Contact for details

Quality Control

Our 1-Octadecanoyl-2-[cis-9-Octadecenoyl]-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and fatty acid profile confirmation, to ensure it meets the stringent requirements for pharmaceutical and research applications. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or waxy solid
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥ 98.0%
Fatty Acid Composition (GC)	Stearic Acid (C18:0): 45-55%; Oleic Acid (C18:1): 45-55%
Solvent Content (Residual Solvents)	Meets ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.