Description

2-(Acetylamino)-2-Deoxy-D-Mannose Tetrakis(Trimethylsilyl) Derivative is a key protected intermediate in carbohydrate and nucleoside chemistry, specifically a fully silylated derivative of N-acetyl-D-mannosamine. This compound is essential for synthetic chemists as it provides a stable, non-polar precursor for glycosylation reactions and the synthesis of complex oligosaccharides and sialic acid derivatives. It is primarily utilized by research institutions and pharmaceutical companies engaged in advanced organic synthesis, glycobiology research, and the development of novel therapeutics and diagnostic agents.

Application

• Glycosylation Reagent: Serves as a crucial building block for the stereoselective synthesis of glycosidic bonds in oligosaccharide and glycoconjugate assembly.
• Sialic Acid Synthesis: Acts as a protected intermediate in the multi-step synthesis of sialic acids and their analogs for biological studies.
• Pharmaceutical Intermediates: Used in the research and development of carbohydrate-based drugs, including antiviral and anticancer agents.
• Glycobiology Research: Employed as a standard or reagent in studies exploring carbohydrate-protein interactions and cell surface recognition.
• Chemical Derivatization: The trimethylsilyl (TMS) groups facilitate solubility in organic solvents and can be selectively removed, enabling further functionalization.
• Nucleoside Chemistry: May be used in the synthesis of modified nucleosides where sugar moiety manipulation is required.

Basic Information

Product Name	2-(Acetylamino)-2-Deoxy-D-Mannose Tetrakis(Trimethylsilyl) Derivative
CAS No.	56298-44-3
Molecular Formula	C20H47NO6Si4
Molecular Weight	522.0 g/mol (approx.)
Synonyms	N-Acetyl-D-mannosamine tetrakis(trimethylsilyl) ether; Per-O-trimethylsilyl-N-acetyl-D-mannosamine; 2-Acetamido-2-deoxy-D-mannose per(trimethylsilyl) ether; 2-Acetamido-2-deoxy-D-mannose, TMS derivative; D-Mannosamine, N-acetyl-, tetrakis(trimethylsilyl) derivative; Fully silylated N-acetylmannosamine; 1,3,4,6-Tetra-O-trimethylsilyl-2-deoxy-2-acetamido-D-mannopyranose
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of 2-(Acetylamino)-2-Deoxy-D-Mannose Tetrakis(Trimethylsilyl) Derivative is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry to confirm identity, purity, and stability. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We adhere to a quality management system to guarantee supply reliability and product consistency for your critical research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent decomposition. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid or viscous oil
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.