Description

L-Homoserine Tris(Trimethylsilyl) Deriv. is a key protected derivative of the non-proteinogenic amino acid L-homoserine, widely used as a crucial synthetic intermediate in advanced organic and peptide chemistry. Its primary value lies in providing a stable, silyl-protected form of the homoserine side chain, enabling precise and efficient multi-step synthesis. This high-purity building block is essential for researchers and manufacturers in pharmaceutical development, agrochemical research, and the production of specialized fine chemicals.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel drug candidates, including enzyme inhibitors and peptide-based therapeutics.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate homoserine residues while protecting reactive functional groups.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the manufacture of chiral compounds, complex natural product analogs, and other high-value specialty chemicals.
• Biochemical Research: Utilized in metabolic pathway studies and the synthesis of labeled compounds for tracer analysis.
• Material Science: Potential precursor for functionalized polymers and advanced organic materials requiring specific amino acid motifs.

Basic Information

Product Name	L-Homoserine Tris(Trimethylsilyl) Deriv.
CAS No.	56273-04-2
Molecular Formula	C13H33NO3Si3
Molecular Weight	347.67 g/mol
Synonyms	L-Homoserine, tris(trimethylsilyl) derivative; (2S)-2-Amino-4-(trimethylsilyloxy)butyric acid bis(trimethylsilyl) ester; Tris(trimethylsilyl) L-homoserinate; N,O,O-Tris(trimethylsilyl)-L-homoserine; L-Homoserine TMS derivative; Protected L-Homoserine; Silylated L-Homoserine
EINECS	Contact for details

Quality Control

Our L-Homoserine Tris(Trimethylsilyl) Deriv. is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for demanding synthetic applications. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.