Description

6-Aminohexanoic Acid Bis(Trimethylsilyl) Deriv. is a silylated derivative of 6-aminohexanoic acid, a key protected intermediate in organic synthesis. This compound is specifically designed to enhance solubility and stability in non-polar media, facilitating critical reactions in sensitive chemical processes. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of peptides, polymers, and complex organic molecules.

Application

• Pharmaceutical Intermediate: Serves as a key protected building block in the synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, pesticides, and plant growth regulators requiring amino acid-derived precursors.
• Polymer Chemistry: Acts as a monomer or chain extender in the production of specialized polyamides and other functional polymers.
• Organic Synthesis Reagent: Facilitates reactions where the free amino and carboxylic acid groups of 6-aminohexanoic acid need protection, such as in Grignard reactions or lithiations.
• Bioconjugation & Linker Chemistry: Employed in the creation of cleavable linkers for drug delivery systems and bioconjugate probes.
• Material Science Research: Used in surface modification and the synthesis of siloxane-based hybrid materials.

Basic Information

Product Name	6-Aminohexanoic Acid Bis(Trimethylsilyl) Deriv.
CAS No.	56272-91-4
Molecular Formula	C12H29NO2Si2
Molecular Weight	275.54 g/mol
Synonyms	6-[(Trimethylsilyl)amino]hexanoic acid trimethylsilyl ester; N,O-Bis(trimethylsilyl)-6-aminohexanoate; ε-Aminocaproic Acid Bis(trimethylsilyl) Deriv.; Hexanoic acid, 6-amino-, bis(trimethylsilyl) deriv.; N,O-Bis(trimethylsilyl)-ε-aminocaproic acid; Silylated 6-AHA; TMS-6-AHA; Protected 6-Aminohexanoate
EINECS	Contact for details

Quality Control

Our 6-Aminohexanoic Acid Bis(Trimethylsilyl) Deriv. is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including GC, HPLC, and NMR to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles for pharmaceutical-grade material upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.