Description

n-(3-Hydroxybenzoyl)Glycine Bis(Trimethylsilyl) Deriv. is a silylated derivative of a glycine-based compound, designed for enhanced stability and solubility in organic synthesis. This specialized reagent is critical for protecting sensitive functional groups and facilitating derivatization in analytical chemistry. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis and analysis of complex organic molecules.

Application

• Derivatization Agent for GC/MS Analysis: Used to enhance the volatility and thermal stability of polar compounds like carboxylic acids and phenols for accurate gas chromatography-mass spectrometry.
• Intermediate in Pharmaceutical Synthesis: Serves as a protected building block in the multi-step synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Protecting Group Chemistry: Employed to temporarily mask hydroxyl and carboxyl groups during complex organic synthesis to prevent unwanted side reactions.
• Agrochemical Research: Used in the development and analysis of novel herbicides, pesticides, and plant growth regulators.
• Material Science Precursor: Acts as a specialty monomer or cross-linking agent in the development of advanced polymers and silicones.
• Metabolite Analysis: Facilitates the identification and quantification of drug metabolites and endogenous compounds in biological matrices.

Basic Information

Product Name	n-(3-Hydroxybenzoyl)Glycine Bis(Trimethylsilyl) Deriv.
CAS No.	56272-74-3
Molecular Formula	C15H25NO3Si2
Molecular Weight	323.54 g/mol
Synonyms	N-(3-Hydroxybenzoyl)glycine bis(trimethylsilyl) ester; Glycine, N-(3-hydroxybenzoyl)-, bis(trimethylsilyl) derivative; 2-[(3-Hydroxybenzoyl)amino]acetic Acid Bis(trimethylsilyl) Ester; Hippuric Acid, 3-Hydroxy-, Bis(trimethylsilyl) Derivative; TMS Derivative of 3-Hydroxyhippuric Acid; Bis(trimethylsilyl) 3-Hydroxyhippurate
EINECS	Contact for details

Quality Control

Our n-(3-Hydroxybenzoyl)Glycine Bis(Trimethylsilyl) Deriv. is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants or an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.