Description

2-Oxooctanoic Acid Bis(Trimethylsilyl) Deriv. is a high-purity, protected keto acid derivative, primarily used as a key synthetic intermediate in advanced organic synthesis. Its value lies in the trimethylsilyl (TMS) protecting groups, which enhance stability and reactivity for precise chemical transformations. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing complex molecules, including active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and plant growth regulators.
• Organic Synthesis Reagent: Serves as a protected keto acid equivalent in nucleophilic addition reactions, aldol condensations, and other carbon-carbon bond-forming processes.
• Peptide Mimetics & Modifications: Facilitates the incorporation of non-natural amino acid structures or side-chain functionalities into peptide chains.
• Material Science Research: Employed as a precursor for synthesizing specialized monomers or ligands for advanced polymers and catalysts.
• Chemical Derivatization for Analysis: Used to prepare volatile derivatives of carboxylic acids for Gas Chromatography-Mass Spectrometry (GC-MS) analysis.

Basic Information

Product Name	2-Oxooctanoic Acid Bis(Trimethylsilyl) Deriv.
CAS No.	56272-73-2
Molecular Formula	C14H30O3Si2
Molecular Weight	302.56 g/mol
Synonyms	2-Oxooctanoic Acid Bis(trimethylsilyl) Ester; 2-Oxooctanoic Acid, Bis(trimethylsilyl) Derivative; 2-Ketooctanoic Acid Bis(TMS) Ester; Hexanoylacetic Acid Bis(trimethylsilyl) Ester; Bis(trimethylsilyl) 2-Oxooctanoate; 2-Oxocaprylic Acid Bis(trimethylsilyl) Ester; α-Ketooctanoic Acid Bis(TMS) Derivative
EINECS	Contact for details

Quality Control

Our 2-Oxooctanoic Acid Bis(Trimethylsilyl) Deriv. is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specification parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for use as a pharmaceutical intermediate.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.