Description

L-Cysteine Tris(Trimethylsilyl) Deriv. is a silylated derivative of the essential amino acid L-Cysteine, designed to enhance stability and reactivity for advanced synthetic applications. This specialized compound is crucial for protecting sensitive functional groups during complex organic and peptide synthesis, preventing unwanted side reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for the production of high-value intermediates and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate Synthesis: Used as a key protected building block in the multi-step synthesis of complex drug molecules and peptides.
• Peptide Chemistry: Serves as a cysteine derivative where the thiol group is protected by trimethylsilyl groups, facilitating controlled deprotection strategies.
• Organic Synthesis Reagent: Employed in reactions requiring a masked thiol functionality, such as nucleophilic substitutions and conjugate additions.
• Bioconjugation Research: Acts as a precursor for creating stable linkages in antibody-drug conjugates (ADCs) and protein labeling.
• Analytical Reference Standard: Used in HPLC and LC-MS methods for the identification and quantification of cysteine derivatives in research samples.
• Material Science: Potential applications in the surface modification of materials and the synthesis of functionalized polymers.

Basic Information

Product Name	L-Cysteine Tris(Trimethylsilyl) Deriv.
CAS No.	56272-69-6
Molecular Formula	C12H29NO2SSi3
Molecular Weight	335.68 g/mol
Synonyms	L-Cysteine tris(trimethylsilyl) ether; N,O,S-Tris(trimethylsilyl)-L-cysteine; Tris(trimethylsilyl) L-cysteinate; Silylated L-Cysteine; Cysteine TMS derivative; (2R)-2-Amino-3-[[trimethylsilyl]thio]-3-(trimethylsilyloxy)-N-(trimethylsilyl)propanamide; Protected L-Cysteine
EINECS	Contact for details

Quality Control

Our L-Cysteine Tris(Trimethylsilyl) Deriv. is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and open flame.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.