Description

2-Hydroxy-2-Methyl-3-Phenylpropanoic Acid is a versatile chiral building block and intermediate in organic synthesis. This compound is valued for its ability to introduce a phenyl-substituted hydroxy acid moiety, which is a key structural feature in various active molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the development of new chemical entities and process optimization.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs), β-blockers, and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging its phenylpropanoic acid backbone.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and specialty polymers requiring specific stereochemistry.
• Academic & Industrial Research: Employed in methodological studies, asymmetric synthesis, and as a standard in analytical chemistry.
• Ligand and Catalyst Development: Useful for creating chiral ligands for metal-catalyzed reactions due to its hydroxyl and carboxylic acid functional groups.

Basic Information

Product Name	2-Hydroxy-2-Methyl-3-Phenylpropanoic Acid
CAS No.	56269-86-4
Molecular Formula	C10H12O3
Molecular Weight	180.20 g/mol
Synonyms	2-Hydroxy-2-methyl-3-phenylpropionic acid; α-Hydroxy-α-methylhydrocinnamic acid; 2-Methyl-2-hydroxy-3-phenylpropanoic acid; Benzenepropanoic acid, α-hydroxy-α-methyl-; (RS)-2-Hydroxy-2-methyl-3-phenylpropionic acid; DL-2-Hydroxy-2-methyl-3-phenylpropanoic acid; Hydrocinnamic acid, α-hydroxy-α-methyl-
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-2-Methyl-3-Phenylpropanoic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support our products with detailed Certificates of Analysis (COA) upon request, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	108°C - 112°C
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Optical Purity (if applicable)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.