Description

Linoleic Acid Trimethylsilyl is a silylated derivative of linoleic acid, a key polyunsaturated fatty acid, designed to enhance stability and volatility for analytical and synthetic applications. This derivative is crucial for protecting the carboxylic acid group during complex organic syntheses, particularly in the production of specialized lipids and pharmaceutical intermediates. It is primarily utilized by researchers and manufacturers in the pharmaceutical, nutraceutical, and advanced materials sectors for gas chromatography (GC) analysis and as a key building block in fine chemical synthesis.

Application

• Derivatization Agent for GC Analysis: Used to convert linoleic acid and related fatty acids into volatile trimethylsilyl (TMS) esters for precise identification and quantification in gas chromatography-mass spectrometry (GC-MS).
• Pharmaceutical Intermediate: Serves as a protected form of linoleic acid in the synthesis of bioactive lipid derivatives, prostaglandins, and other specialized therapeutic agents.
• Nutraceutical & Cosmetic Ingredient Synthesis: Acts as a key precursor in the manufacturing of stabilized, high-purity fatty acid derivatives for dietary supplements and advanced skincare formulations.
• Polymer & Material Science: Employed in the synthesis of specialty monomers and polymers, contributing to the development of materials with specific hydrophobic or release properties.
• Biochemical Research: Essential in metabolic studies and lipidomics research for tracing and analyzing fatty acid metabolism and pathways.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories to calibrate instruments and validate analytical methods for fatty acid content.

Basic Information

Product Name	Linoleic Acid Trimethylsilyl
CAS No.	56259-07-5
Molecular Formula	C21H40O2Si
Molecular Weight	352.63 g/mol
Synonyms	Linoleic Acid TMS Ester; (9Z,12Z)-Octadeca-9,12-dienoic Acid Trimethylsilyl Ester; Trimethylsilyl Linoleate; TMS-Linoleate; Linoleic Acid Trimethylsilyl Derivative; 9,12-Linoleic Acid Trimethylsilyl Ester; cis,cis-9,12-Octadecadienoic Acid Trimethylsilyl Ester
EINECS	Contact for details

Quality Control

Our Linoleic Acid Trimethylsilyl is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (IR, NMR), to ensure high chemical purity and identity. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment to guarantee traceability and compliance with your research or manufacturing specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 95.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.