Description

1-O,3-O,4-O,5-O,6-o-Pentakis(Trimethylsilyl)-D-Fructose o-Methyl Oxime is a highly derivatized, silylated carbohydrate derivative used as a key synthetic intermediate and analytical standard. This compound matters for its role in protecting hydroxyl groups during complex organic synthesis, enabling precise chemical transformations in sensitive molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel compounds and for use in chromatographic analysis.

Application

• Pharmaceutical Intermediate: Used in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Analytical Standard: Serves as a high-purity reference standard for Gas Chromatography (GC) and Gas Chromatography-Mass Spectrometry (GC-MS) analysis of sugar derivatives.
• Carbohydrate Chemistry Research: A critical reagent for studying and modifying sugar structures, protecting hydroxyl groups to direct regioselective reactions.
• Glycoconjugate Synthesis: Employed in the preparation of sophisticated glycoconjugates for biochemical and medicinal research.
• Process Development: Utilized in scaling up synthetic routes that require temporary protection of multiple hydroxyl functionalities.
• Fine Chemical Production: Acts as a building block for the manufacture of specialty chemicals with specific chiral configurations.

Basic Information

Product Name	1-O,3-O,4-O,5-O,6-o-Pentakis(Trimethylsilyl)-D-Fructose o-Methyl Oxime
CAS No.	56196-14-6
Molecular Formula	C23H55NO6Si5
Molecular Weight	610.22 g/mol
Synonyms	D-Fructose, O-methyloxime, pentakis(trimethylsilyl) ether; Pentakis-O-(trimethylsilyl)-D-fructose O-methyloxime; D-Fructose O-methyloxime pentatrimethylsilyl ether; 1,3,4,5,6-Penta-O-trimethylsilyl-D-fructose O-methyloxime; TMS-derivatized D-fructose methyloxime; Per-TMS D-fructose methyloxime
EINECS	Contact for details

Quality Control

Our 1-O,3-O,4-O,5-O,6-o-Pentakis(Trimethylsilyl)-D-Fructose o-Methyl Oxime is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and structural identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.