Description

2-Amino-2-Deoxy-D-Glucose Tetrakis(Trimethylsilyl) Derivative is a key protected derivative of glucosamine, a fundamental amino sugar. This compound is essential for synthetic chemists as it provides a versatile, silylated intermediate with enhanced solubility and stability for complex carbohydrate and nucleoside synthesis. It is primarily utilized by research institutions and pharmaceutical development teams working on glycobiology, antiviral agents, and advanced material science.

Application

• Glycoconjugate Synthesis: A crucial protected building block for the chemical synthesis of complex oligosaccharides, glycopeptides, and glycolipids.
• Pharmaceutical Intermediates: Serves as a key precursor in the research and development of novel antiviral and antibacterial agents that target carbohydrate-processing pathways.
• Chemical Derivatization for Analysis: Used to prepare volatile derivatives for Gas Chromatography-Mass Spectrometry (GC-MS) analysis of amino sugars and related metabolites.
• Material Science Research: Employed in the synthesis of functionalized polymers and surfaces with specific carbohydrate motifs for biosensing or biocompatibility studies.
• Biochemical Tool Development: Acts as a substrate or inhibitor analog in enzymatic studies related to glycosyltransferases and glycosidases.
• Standards and Reference Materials: Provides a high-purity standard for analytical method development and quality control in carbohydrate chemistry.

Basic Information

Product Name	2-Amino-2-Deoxy-D-Glucose Tetrakis(Trimethylsilyl) Derivative
CAS No.	56193-55-6
Molecular Formula	C18H47NO5Si4
Molecular Weight	493.92 g/mol
Synonyms	D-Glucosamine, N,O,O',O'',O'''-tetrakis(trimethylsilyl)-; Per(trimethylsilyl)-D-glucosamine; 2-Amino-2-deoxy-D-glucose per(trimethylsilyl) ether; Tetrakis-O-(trimethylsilyl)-D-glucosamine; Fully silylated D-glucosamine; Glucosamine TMS derivative; 1,3,4,5,6-Penta-O-trimethylsilyl-2-deoxy-2-(trimethylsilylamino)-D-glucitol; Amino sugar TMS ether
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-2-Deoxy-D-Glucose Tetrakis(Trimethylsilyl) Derivative is manufactured and tested under strict quality management systems. We ensure high chemical purity and structural integrity through comprehensive analytical techniques including NMR, HPLC, and GC-MS. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee batch-to-batch consistency for your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere (argon or nitrogen) after each use to prevent decomposition. Keep away from heat and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 95% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.