Description

(E)-3-(3-Methoxyphenyl)-2-Propenoyl Chloride is a high-purity, reactive chemical intermediate featuring an α,β-unsaturated carbonyl chloride moiety. This compound is valued for its role as a versatile acylating and building block agent in advanced organic synthesis, enabling the introduction of the (E)-3-(3-methoxyphenyl)propenoyl group. It is primarily sought by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules, including potential active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those requiring a cinnamoyl chloride derivative structure.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the methoxyphenylpropenoyl moiety is integral to biological activity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing specialized organic compounds used in electronic displays and photonic devices.
• Polymer Modification Agent: Employed to introduce specific functional groups into polymer chains to alter material properties like adhesion, solubility, or reactivity.
• Peptide & Protein Conjugation: Acts as an acylating agent for modifying amino acids, peptides, or other biomolecules in biochemical research.
• Fine Chemical & Flavor/Fragrance Intermediate: Utilized in the multi-step synthesis of complex aromatic compounds for specialty applications.

Basic Information

Product Name	(E)-3-(3-Methoxyphenyl)-2-Propenoyl Chloride
CAS No.	56030-38-7
Molecular Formula	C10H9ClO2
Molecular Weight	196.63 g/mol
Synonyms	(E)-3-(3-Methoxyphenyl)acryloyl chloride; trans-3-(3-Methoxyphenyl)propenoyl chloride; (E)-3-(m-Methoxyphenyl)acryloyl chloride; 3-(3-Methoxyphenyl)-2-propenoyl chloride, (E)-; (2E)-3-(3-Methoxyphenyl)prop-2-enoyl chloride; m-Methoxycinnamoyl chloride; 3-Methoxycinnamoyl chloride
EINECS	Contact for details

Quality Control

Our (E)-3-(3-Methoxyphenyl)-2-Propenoyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.