Description

Buflomedil is a vasoactive pharmaceutical compound with the CAS registry number 55837-25-7. This active pharmaceutical ingredient (API) is valued for its role in improving peripheral and cerebral circulation by acting as an α-adrenergic receptor antagonist. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of medications for vascular disorders. Our supply ensures high purity and consistent quality for critical formulation needs.

Application

• Pharmaceutical API: Primary use as the active ingredient in finished dosage forms for the treatment of peripheral vascular diseases.
• Vasodilator Formulations: Key component in medications designed to alleviate symptoms of intermittent claudication and Raynaud's phenomenon.
• Cerebral Circulation Therapy: Used in the development of drugs aimed at treating cognitive disorders associated with reduced cerebral blood flow.
• Research & Development: Serves as a reference standard and building block in pharmacological and pharmacokinetic studies.
• Generic Drug Manufacturing: Essential for companies producing generic versions of vasoactive medications containing Buflomedil HCl.

Basic Information

Product Name	Buflomedil
CAS No.	55837-25-7
Molecular Formula	C17H25NO4
Molecular Weight	307.39 g/mol
Synonyms	Buflomedil; Buflomedil base; 2',4',6'-Trimethoxy-4-(1-pyrrolidinyl)butyrophenone; 4-(1-Pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-1-butanone; Loftyl; Fonzylane; Buflomedil HCl (Hydrochloride salt); Buflomedil Pyridoxal Phosphate
EINECS	Contact for details

Quality Control

Our Buflomedil is manufactured under strict quality management systems to ensure it meets the stringent requirements for pharmaceutical intermediates and APIs. Quality is verified through comprehensive analytical testing, including identification, purity assays, and impurity profiling. A Certificate of Analysis (COA) is provided with each batch, detailing compliance with agreed specifications. We support compliance with major pharmacopoeial standards (e.g., USP, EP) and regulatory frameworks (ICH Q7, GMP) for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.