Description

3-Piperazin-1-Yl-1H-Quinoxalin-2-One is a high-purity, heterocyclic organic compound of significant interest in advanced chemical synthesis. This specialized intermediate is valued for its unique molecular scaffold, which is crucial for developing novel compounds with targeted biological activity. It is primarily sought after by research institutions and pharmaceutical development companies engaged in medicinal chemistry and the creation of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key building block in the research and synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Biochemical Research: Employed in the development of enzyme inhibitors or receptor modulators due to its quinoxalinone-piperazine structure.
• Agrochemical Development: Potential intermediate in the synthesis of new crop protection agents and pesticides.
• Material Science: Investigated for use in the synthesis of organic electronic materials or advanced polymers.

Basic Information

Product Name	3-Piperazin-1-Yl-1H-Quinoxalin-2-One
CAS No.	55686-32-3
Molecular Formula	C₁₂H₁₄N₄O
Molecular Weight	230.27 g/mol
Synonyms	3-(Piperazin-1-yl)quinoxalin-2(1H)-one; 1H-Quinoxalin-2-one, 3-(1-piperazinyl)-; 3-(1-Piperazinyl)-1H-quinoxalin-2-one; 3-Piperazinylquinoxalin-2(1H)-one; Quinoxalin-2-one, 3-piperazinyl-; 55686-32-3; UNII-2K4F6T8Q4R
EINECS	Contact for details

Quality Control

Our 3-Piperazin-1-Yl-1H-Quinoxalin-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality attributes. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.