Description

3-Chloropyrazine-2-Carbonitrile is a versatile and high-value heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key precursor in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and functional materials.

Application

• Pharmaceutical Intermediate: A critical synthon for the synthesis of novel drug candidates, including kinase inhibitors and other biologically active heterocycles.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the pyrazine core for bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold for constructing complex molecular libraries in medicinal and combinatorial chemistry.
• Material Science Precursor: Potential use in the synthesis of specialty polymers, ligands for catalysis, and electronic materials.
• Cross-Coupling Reactions: The chlorine and nitrile groups offer orthogonal reactivity for palladium-catalyzed cross-coupling and further functionalization.

Basic Information

Product Name	3-Chloropyrazine-2-Carbonitrile
CAS No.	55557-52-3
Molecular Formula	C5H2ClN3
Molecular Weight	139.54 g/mol
Synonyms	2-Chloro-3-cyanopyrazine; 3-Chloro-2-cyanopyrazine; 2-Cyano-3-chloropyrazine; 3-Chloropyrazinecarbonitrile; Pyrazine-2-carbonitrile, 3-chloro-; 3-Chloro-2-pyrazinecarbonitrile
EINECS	Contact for details

Quality Control

Our 3-Chloropyrazine-2-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.